Page 68 - CIBERDEM-2015-eng

Research groups
Metabolic and molecular disturbances
in diabetes
Programme: P2
Lead Researcher: Novials Sardá, Anna Maria
Group members
STAFF MEMBERS: Brugnara, Laura | Castaño Perez, Carlos | Murillo García, Serafín
ASSOCIATED MEMBERS: Alcarraz Vizán, Gema | Cadavez Trigo, Lisa | Ceriello, Antonio | García Rovés González, Pablo Miguel | Montane Mogas, Joel | Moreno Asso, Alba | Parrizas Jiménez, Marcelina | Servitja Duque, Joan Marc | Visa Majoral, Montse.
Main lines of research
• Mechanisms of pancreatic islet dysfunction in type 2 diabetes mellitus, in particular, the process of cytotoxicity as induced by amyloidogenesis.
• Signalling and transcriptional networks in the pancreatic beta cell, mainly related to the mod- ulation of the transcriptional programme under stress conditions.
• Impact of lifestyle on diabetes: metabolic and molecular responses to exercise and nutrition in diabetic patients and animal models.
• Impact of glucose oscillations on cardiovascular complications of diabetes: mechanisms of en- dothelial dysfunction.
68 I Annual report 2015 I CIBERDEM