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Research groups
Transcriptional mechanisms
of pancreatic function
Programme: P2
Lead Researcher: Vallejo Fernández de la Reguera, Mario
Group members
STAFF MEMBERS: Fernández Pérez, Antonio | Mirasierra Cuevas, Mercedes. Main lines of research
• The characterization of phenotypic alterations of pancreatic islets in the absence of the homeopro- tein Alx3.
• The requirement of Alx3 for the maintenance of glucose homeostasis and metabolic activity in vivo.
• •
The identification of transcriptional targets regu- lated by Alx3.
Alx3 and diabetic pregnancy: the role of Alx3 in the regulation of the development of the neural tube and vulnerability to hyperglycaemic insult in its absence.
76 I Annual report 2015 I CIBERDEM
