Page 29 - CIBERDEM-2015-eng

Research groups
Most relevant scientific articles
MASANA L., CABRE A., HERAS M., AMIGO N., CORREIG X., MARTíNEZ-HERVAS S. ET AL. Remarkable quantitative and qualitative differences in HDL after niacin or fenofi- brate therapy in type 2 diabetic patients. Atherosclerosis. 2015;238(2):213-219.
MARTíNEZ-BARQUERO V., DE MARCO G., MARTíNEZ-HERVAS S., RENTERO P., GALAN-CHILET I., BLESA S. ET AL. Polymor- phisms in endothelin system genes, arsenic levels and obesity risk. PLoS ONE. 2015;10(3).
MORA M., ADAM V., PALOMERA E., BLESA S., DíAZ G., BUQUET X. ET AL. Ghrelin gene variants influence on metabolic syndrome components in aged Spanish population. PLoS ONE. 2015;10(9).
MANSEGO M.L., DE MARCO G., IVORRA C., LóPEZ-IZQUIERDO R., MORCILLO S., ROJO-MARTíNEZ G. ET AL. The nutrigenetic influence of the interaction between dietary vitamin E and TXN and COMT gene polymorphisms on waist circumfer- ence: A case control study. Journal of Translational Med-
GALAN-CHILET I, GUALLAR E, MARTIN-ESCUDERO JC, DE MAR- CO G, DOMíNGUEZ-LUCAS A, GONZáLEZ-MANZANO I ET AL. Do Genes Modify the Association of Selenium and Lipid Levels?. Antioxidants & redox signaling. 2015.
Highlights
The scientific research activity of the group during 2015 included the launch of two competitive and multidisciplinary research projects. On the one hand, the Project “Immunopharmacological modulation of the systemic inflammation associated to metabolic disorders. Search for new therapeutic targets and synthesis of novel drugs”. This project deals with the study of the role of CCL11 / CCR3 axis in systemic inflammation associated with familial hypercholes- terolemia and immunomodulation oral fat overload, and the study of the role of CXCL16 axis / CXCR6 on
icine. 2015;13(1).
endothelial dysfunction induced by Ang-II and sub- jects with metabolic síndrome. On the other hand, the Project “MicroRNAs in insulin-resistant obese children. Diagnostic, prognostic and therapeutic implications on early vascular damage”. The main objetives for this study is to determine the pattern of microRNAs in obese children with and without insulin resistance (IR), analyzing the relationship be- tween the miroRNA patterns and vascular, inflam- matory and oxidative stress alterations, as well as their variations after nutritional intervention.
Institution: Fund. para la Investigación del Hospital Clínico de la Comunidad Valenciana (Fundación INCLIVA) Contact: Instituto de Investigación Sanitaria Incliva · Av Blasco Ibáñez, 17. 46010 Valencia
Tel.: 96 197 35 36 · E.mail: [email protected]
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