Page 48 - CIBERDEM-2015-eng
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Research groups
Diabetes, obesity and human reproduction
Programme: P3
Lead Researcher: Escobar Morreale, Héctor Francisco
Group members
STAFF MEMBERS: Fernández Durán, Elena | Insenser Nieto, María Rosa | Martínez García, Ma Ángeles. ASSOCIATED MEMBERS: Álvarez Blasco, Francisco | Luque Ramírez, Manuel | Roldán Martín, María Belén |
San Millán López, José Luis | Sanchón Rodríguez, Raúl.
Main lines of research
Influence of sex hormones on the development of abdominal adiposity and visceral adipose tissue dysfunction in humans as pathogenetic factors of insulin resistance and diabetes, including:
• an integrated approach to the influence of sex hormones on the amount and dysfunction of vis- ceral and subcutaneous fat as studied by clinical research, molecular genetics, molecular biology, transcriptomics, proteomics and metabolomics.
• the identification of pathogenetic markers of di- abetes in severe obesity and predictors of diabe- tes remission after bariatric surgery.
• the role of disordered iron metabolism on the metabolic associations of polycystic ovary syn- drome.
• the effects of sex hormones on the metabolic and inflammatory responses to the oral admin- istration of different macronutrients.
• influence of treatment of gonadal dysfunction (polycystic ovary syndrome or functional hypog- onadotrophic hypogonadism) on visceral adipos- ity and intermediate metabolism.
48 I Annual report 2015 I CIBERDEM
